YWHAH

Across TCGA cell cohorts, YWHAH RNA expression is significantly associated with the go_rna of many other GO terms, with 4,113 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible YWHAH-associated GO terms across cancer lineages are Protein depolymerization, Interleukin-34-mediated signaling pathway, and Protein localization to microtubule plus-end. Each is linked with YWHAH in more than 14 cancer types. Because this analysis shows association rather than direction, both YWHAH-to-partner and partner-to-YWHAH results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein depolymerization grouped by YWHAH-low versus YWHAH-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (YWHAH→partner) and Y-score (partner→YWHAH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Protein depolymerization →	+0.120	+0.936	.009	.008	3	15
OVARY	Interleukin-34-mediated signaling pathway →	+0.230	+1.222	<.001	<.001	3	14
SOFT_TISSUE	Protein localization to microtubule plus-end →	+0.209	+0.732	<.001	<.001	3	13
SOFT_TISSUE	Protein localization to microtubule end →	+0.209	+0.732	<.001	<.001	3	13
OVARY	Regulation of anaphase-promoting complex-dependent catabolic process →	+0.087	+0.694	.003	.004	3	13
BONE	Regulation of chromosome condensation →	+0.161	+0.611	.007	.004	2	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,113 associations by consensus.

Protein depolymerization by YWHAH expression — URINARY_TRACT

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