YWHAG

Across TCGA patient cohorts, YWHAG mutation is significantly associated with the RNA expression of many other genes, with 701 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible YWHAG-associated genes across cancer lineages are RNU6-215P, MIR6803, and RNA5SP205. Each is linked with YWHAG in more than 1 cancer types. Because this analysis shows association rather than direction, both YWHAG-to-partner and partner-to-YWHAG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-215P grouped by YWHAG-low versus YWHAG-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (YWHAG→partner) and Y-score (partner→YWHAG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RNU6-215P →	+0.242	+7.731	<.001	.009	3	2
UCEC	MIR6803 →	+0.124	+4.156	<.001	.004	3	2
UCEC	RNA5SP205 →	+0.132	+2.682	.006	.004	3	2
UCEC	MIR1251 →	+0.134	+3.807	.001	.001	3	2
SKCM	SNRPGP8 →	+0.146	+4.867	<.001	.005	3	2
BLCA	OR11J5P →	+0.119	+7.640	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 701 associations by consensus.

RNU6-215P by YWHAG expression — BRCA

Explore this box plot interactively →