YWHAG

Across TCGA cell cohorts, YWHAG RNA expression is significantly associated with the go_rna of many other GO terms, with 3,294 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible YWHAG-associated GO terms across cancer lineages are Peptidyl-glutamic acid carboxylation, Protein carboxylation, and Positive regulation of isotype switching to IgG isotypes. Each is linked with YWHAG in more than 13 cancer types. Because this analysis shows association rather than direction, both YWHAG-to-partner and partner-to-YWHAG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Peptidyl-glutamic acid carboxylation grouped by YWHAG-low versus YWHAG-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (YWHAG→partner) and Y-score (partner→YWHAG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Peptidyl-glutamic acid carboxylation →	+0.116	+0.888	<.001	<.001	3	14
BREAST	Protein carboxylation →	+0.116	+0.888	<.001	<.001	3	14
BONE	Positive regulation of isotype switching to IgG isotypes →	+0.116	+0.670	.004	.002	3	12
LIVER	2-oxoglutarate decarboxylation to succinyl-CoA →	+0.108	+0.619	<.001	.001	3	11
OVARY	Nucleic acid transport →	+0.076	+0.704	.003	.008	3	10
OVARY	RNA transport →	+0.076	+0.704	.003	.008	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,294 associations by consensus.

Peptidyl-glutamic acid carboxylation by YWHAG expression — BREAST

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