YWHAEP4

Across TCGA patient cohorts, YWHAEP4 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,922 significant associations in total. STAD shows the largest number of these associations.

The most reproducible YWHAEP4-associated GO terms across cancer lineages are Positive regulation of DNA biosynthetic process, Regulation of telomere maintenance, and RNA capping. Each is linked with YWHAEP4 in more than 5 cancer types. Because this analysis shows association rather than direction, both YWHAEP4-to-partner and partner-to-YWHAEP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of DNA biosynthetic process grouped by YWHAEP4-low versus YWHAEP4-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (YWHAEP4→partner) and Y-score (partner→YWHAEP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of DNA biosynthetic process →	+0.079	+0.057	<.001	<.001	3	6
STAD	Regulation of telomere maintenance →	+0.077	+0.060	<.001	<.001	3	6
STAD	RNA capping →	+0.074	+0.062	<.001	<.001	3	6
STAD	Regulation of telomerase activity →	+0.072	+0.060	<.001	<.001	3	5
BLCA	Stress-induced premature senescence →	+0.065	+0.020	.001	.005	2	6
STAD	Regulation of telomere capping →	+0.062	+0.063	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,922 associations by consensus.

Positive regulation of DNA biosynthetic process by YWHAEP4 expression — STAD

Explore this box plot interactively →