YWHAEP1

Across TCGA patient cohorts, YWHAEP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,870 significant associations in total. THYM shows the largest number of these associations.

The most reproducible YWHAEP1-associated GO terms across cancer lineages are Positive regulation of mRNA processing, Ribosomal subunit export from nucleus, and Maturation of LSU-rRNA. Each is linked with YWHAEP1 in more than 28 cancer types. Because this analysis shows association rather than direction, both YWHAEP1-to-partner and partner-to-YWHAEP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of mRNA processing grouped by YWHAEP1-low versus YWHAEP1-high in DLBC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (YWHAEP1→partner) and Y-score (partner→YWHAEP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	Positive regulation of mRNA processing →	+0.078	+0.201	.002	<.001	3	29
UVM	Ribosomal subunit export from nucleus →	+0.060	+0.115	<.001	<.001	3	27
ESCA	Maturation of LSU-rRNA →	+0.066	+0.356	.005	.001	3	26
UVM	RNA methylation →	+0.043	+0.160	<.001	<.001	3	26
UVM	rRNA metabolic process →	+0.039	+0.125	<.001	<.001	3	26
UCS	Positive regulation of mRNA 3'-end processing →	+0.085	+0.816	<.001	<.001	2	27

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,870 associations by consensus.

Positive regulation of mRNA processing by YWHAEP1 expression — DLBC

Explore this box plot interactively →