YWHABP2

Across TCGA patient cohorts, YWHABP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,122 significant associations in total. STAD shows the largest number of these associations.

The most reproducible YWHABP2-associated GO terms across cancer lineages are Positive regulation of post-translational protein modification, Negative regulation of protein catabolic process, and Regulation of mRNA splicing, via spliceosome. Each is linked with YWHABP2 in more than 30 cancer types. Because this analysis shows association rather than direction, both YWHABP2-to-partner and partner-to-YWHABP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of post-translational protein modification grouped by YWHABP2-low versus YWHABP2-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (YWHABP2→partner) and Y-score (partner→YWHABP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Positive regulation of post-translational protein modification →	+0.048	+0.344	<.001	<.001	3	31
STAD	Negative regulation of protein catabolic process →	+0.047	+0.330	<.001	<.001	3	31
ESCA	Regulation of mRNA splicing, via spliceosome →	+0.057	+0.293	<.001	<.001	3	31
ESCA	Positive regulation of protein ubiquitination →	+0.048	+0.431	<.001	<.001	3	30
ESCA	Regulation of mRNA processing →	+0.056	+0.309	<.001	<.001	3	30
ESCA	Epigenetic regulation of gene expression →	+0.055	+0.388	<.001	<.001	3	30

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,122 associations by consensus.

Positive regulation of post-translational protein modification by YWHABP2 expression — ESCA

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