Across TCGA cell cohorts, YTHDF3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,387 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible YTHDF3-associated GO terms across cancer lineages are Stress granule assembly, Vacuolar transport, and Negative regulation of protein localization to centrosome. Each is linked with YTHDF3 in more than 14 cancer types. Because this analysis shows association rather than direction, both YTHDF3-to-partner and partner-to-YTHDF3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (YTHDF3→partner) and Y-score (partner→YTHDF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Stress granule assembly →	+0.120	+0.775	.002	.001	3	15
CNS	Vacuolar transport →	+0.045	+0.567	<.001	<.001	3	15
BLOOD_Myeloma	Negative regulation of protein localization to centrosome →	+0.126	+0.816	<.001	<.001	3	14
LIVER	Regulation of protein lipidation →	+0.130	+0.563	<.001	.001	3	14
OESOPHAGUS	Positive regulation of translational initiation →	+0.149	+0.941	.007	.003	3	14
CNS	Lysosomal transport →	+0.043	+0.356	<.001	.008	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,387 associations by consensus.

Exploration

YTHDF3 survival (RNA) · tumor vs normal (RNA) · all YTHDF3 data types