YTHDF2P1

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, YTHDF2P1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,155 significant associations in total. STAD shows the largest number of these associations.

The most reproducible YTHDF2P1-associated GO terms across cancer lineages are Positive regulation of mRNA processing, Maturation of SSU-rRNA, and mRNA 3'-end processing. Each is linked with YTHDF2P1 in more than 31 cancer types. Because this analysis shows association rather than direction, both YTHDF2P1-to-partner and partner-to-YTHDF2P1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of mRNA processing grouped by YTHDF2P1-low versus YTHDF2P1-high in UVM.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (YTHDF2P1→partner) and Y-score (partner→YTHDF2P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UVMPositive regulation of mRNA processing →+0.073+0.835<.001<.001332
DLBCMaturation of SSU-rRNA →+0.069+0.565.003<.001331
STADmRNA 3'-end processing →+0.068+0.270<.001<.001331
DLBCPositive regulation of mRNA 3'-end processing →+0.072+0.443<.001<.001331
DLBCEndonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →+0.075+0.534.001<.001331
DLBCXMP metabolic process →+0.089+0.456<.001<.001330
Each partner links to its Q-omics profile. Showing the 6 strongest of 7,155 associations by consensus.

Positive regulation of mRNA processing by YTHDF2P1 expression — UVM

Box plot of Positive regulation of mRNA processing in YTHDF2P1-low vs YTHDF2P1-high samples in UVM.

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Exploration