YTHDF1

Across TCGA patient cohorts, YTHDF1 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,009 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible YTHDF1-associated proteins across cancer lineages are STAU1, CSE1L, and LSM14B. Each is linked with YTHDF1 in more than 6 cancer types. Because this analysis shows association rather than direction, both YTHDF1-to-partner and partner-to-YTHDF1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, YTHDF1 versus STAU1 in COAD, with a Pearson correlation of 0.48.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (YTHDF1→partner) and Y-score (partner→YTHDF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	STAU1 →	+0.298	+0.514	<.001	<.001	3	7
UCEC	CSE1L →	+0.389	+0.358	<.001	.002	3	7
LUAD	LSM14B →	+0.456	+0.513	<.001	<.001	3	6
LSCC	CSTF1 →	+0.269	+0.564	<.001	<.001	3	6
LSCC	PUS7 →	+0.451	+0.517	<.001	<.001	3	6
LSCC	AAR2 →	+0.199	+0.388	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,009 associations by consensus.

YTHDF1 vs STAU1 — COAD

Explore this scatter interactively →