YTHDC1

Across TCGA patient cohorts, YTHDC1 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,139 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible YTHDC1-associated proteins across cancer lineages are FKBP11, SDF2L1, and SEC24A. Each is linked with YTHDC1 in more than 5 cancer types. Because this analysis shows association rather than direction, both YTHDC1-to-partner and partner-to-YTHDC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, YTHDC1 versus FKBP11 in LUAD, with a Pearson correlation of -0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (YTHDC1→partner) and Y-score (partner→YTHDC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	FKBP11 →	-0.623	-0.312	<.001	<.001	3	6
CCRCC	SDF2L1 →	-0.471	-0.341	<.001	<.001	3	5
CCRCC	SEC24A →	-0.271	-0.291	<.001	<.001	3	5
BRCA	SND1 →	-0.284	-0.497	<.001	<.001	3	5
CCRCC	CKAP4_S26 →	-0.932	-0.456	<.001	<.001	3	5
CCRCC	COPB2 →	-0.194	-0.385	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,139 associations by consensus.

YTHDC1 vs FKBP11 — LUAD

Explore this scatter interactively →