YTHDC1

Across TCGA patient cohorts, YTHDC1 protein abundance is significantly associated with the protein abundance of many other proteins, with 29,991 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible YTHDC1-associated proteins across cancer lineages are ZFR, RBM12, and RBM14. Each is linked with YTHDC1 in more than 9 cancer types. Because this analysis shows association rather than direction, both YTHDC1-to-partner and partner-to-YTHDC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, YTHDC1 versus ZFR in GBM, with a Pearson correlation of 0.80.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (YTHDC1→partner) and Y-score (partner→YTHDC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ZFR →	+0.348	+0.439	<.001	<.001	3	10
GBM	RBM12 →	+0.358	+0.377	<.001	<.001	3	10
GBM	RBM14 →	+0.345	+0.384	<.001	<.001	3	10
GBM	PHF5A →	+0.384	+0.297	<.001	<.001	3	10
LSCC	PRPF3 →	+0.384	+0.271	<.001	<.001	3	10
GBM	PRPF40A →	+0.317	+0.322	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 29,991 associations by consensus.

YTHDC1 vs ZFR — GBM

Explore this scatter interactively →