Across TCGA patient cohorts, YRDC RNA expression is significantly associated with the protein abundance of many other proteins, with 12,350 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible YRDC-associated proteins across cancer lineages are YRDC_S37, CTPS1, and KIF2C. Each is linked with YRDC in more than 7 cancer types. Because this analysis shows association rather than direction, both YRDC-to-partner and partner-to-YRDC results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (YRDC→partner) and Y-score (partner→YRDC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	YRDC_S37 →	+0.486	+0.845	<.001	<.001	3	8
OV	CTPS1 →	+0.455	+0.517	<.001	<.001	3	7
LUAD	KIF2C →	+0.652	+0.322	<.001	.002	3	7
UCEC	PURA →	-0.402	-0.883	<.001	.001	3	6
LSCC	HAT1 →	+0.532	+0.544	<.001	<.001	3	6
BRCA	CDC20_T70 →	+1.127	+0.638	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,350 associations by consensus.

Exploration

YRDC survival (RNA) · tumor vs normal (RNA) · all YRDC data types