YRDC

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, YRDC RNA expression is significantly associated with the go_rna of many other GO terms, with 2,941 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible YRDC-associated GO terms across cancer lineages are Maturation of SSU-rRNA, tRNA processing, and Regulation of translational fidelity. Each is linked with YRDC in more than 13 cancer types. Because this analysis shows association rather than direction, both YRDC-to-partner and partner-to-YRDC results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (YRDC→partner) and Y-score (partner→YRDC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LymphomaMaturation of SSU-rRNA →+0.146+0.886<.001<.001314
OESOPHAGUStRNA processing →+0.048+0.840.002.006312
SKINRegulation of translational fidelity →+0.066+0.429<.001.001312
SKINMitochondrial large ribosomal subunit assembly →+0.072+0.523<.001<.001312
BLOOD_LymphomaMaturation of 5.8S rRNA →+0.110+0.908<.001<.001312
UPPER_AERODIGESTIVE_TRACTDNA-templated transcription initiation →+0.063+0.569.003.003312
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,941 associations by consensus.

Exploration