YPEL5

Across TCGA cell cohorts, YPEL5 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible YPEL5-associated genes across cancer lineages are ACER1, EIF4E1B, and PRAMEF20. Each is linked with YPEL5 in more than 1 cancer types. Because this analysis shows association rather than direction, both YPEL5-to-partner and partner-to-YPEL5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ACER1 grouped by YPEL5-low versus YPEL5-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (YPEL5→partner) and Y-score (partner→YPEL5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ACER1 →	+0.096	+3.823	.001	.006	3	1
LARGE_INTESTINE	EIF4E1B →	+0.127	+4.029	<.001	.004	3	1
LARGE_INTESTINE	PRAMEF20 →	+0.012	+4.437	<.001	.004	3	1
LARGE_INTESTINE	GSG1L2 →	+0.016	+4.437	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

ACER1 by YPEL5 expression — LARGE_INTESTINE

Explore this box plot interactively →