YPEL1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, YPEL1 mutation is significantly associated with the RNA expression of many other genes, with 1,156 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible YPEL1-associated genes across cancer lineages are RNU6-1093P, LINC02394, and LINC01898. Each is linked with YPEL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both YPEL1-to-partner and partner-to-YPEL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1093P grouped by YPEL1-low versus YPEL1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (YPEL1→partner) and Y-score (partner→YPEL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMRNU6-1093P →+0.666+5.292<.001.00632
BLCALINC02394 →+0.118+5.411<.001.00531
BLCALINC01898 →+0.040+5.329<.001.00631
BLCANOS2P1 →+0.034+5.177<.001.00731
BLCAMIR4676 →+0.547+5.788<.001.00331
BLCAREXO1L8P →+0.046+5.497<.001.00431
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,156 associations by consensus.

RNU6-1093P by YPEL1 expression — SKCM

Box plot of RNU6-1093P in YPEL1-low vs YPEL1-high samples in SKCM.

Explore this box plot interactively →

Exploration