YOD1

Across TCGA patient cohorts, YOD1 mutation is significantly associated with the RNA expression of many other genes, with 4,766 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible YOD1-associated genes across cancer lineages are ATP6V1G1P4, RN7SL191P, and HIGD1AP9. Each is linked with YOD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both YOD1-to-partner and partner-to-YOD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATP6V1G1P4 grouped by YOD1-low versus YOD1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (YOD1→partner) and Y-score (partner→YOD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATP6V1G1P4 →	+0.186	+1.444	.001	.004	3	2
UCEC	RN7SL191P →	+0.123	+2.134	<.001	.001	3	2
UCEC	HIGD1AP9 →	+0.215	+1.785	.002	<.001	3	2
BRCA	MIR6515 →	+0.717	+8.055	<.001	.007	3	1
UCEC	FAM219B →	+0.498	+3.180	<.001	<.001	3	1
UCEC	MSC →	+0.551	+2.233	.009	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,766 associations by consensus.

ATP6V1G1P4 by YOD1 expression — UCEC

Explore this box plot interactively →