YME1L1

Across TCGA cell cohorts, YME1L1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,684 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible YME1L1-associated GO terms across cancer lineages are Negative regulation of beige fat cell differentiation, Positive regulation of chromosome condensation, and Ubiquitin-dependent protein catabolic process via the C-end degron rule pathway. Each is linked with YME1L1 in more than 11 cancer types. Because this analysis shows association rather than direction, both YME1L1-to-partner and partner-to-YME1L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of beige fat cell differentiation grouped by YME1L1-low versus YME1L1-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (YME1L1→partner) and Y-score (partner→YME1L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Negative regulation of beige fat cell differentiation →	+0.116	+0.707	<.001	<.001	3	12
SOFT_TISSUE	Positive regulation of chromosome condensation →	+0.157	+0.490	<.001	<.001	3	11
OESOPHAGUS	Ubiquitin-dependent protein catabolic process via the C-end degron rule pathway →	+0.119	+0.562	<.001	.006	3	11
UPPER_AERODIGESTIVE_TRACT	Positive regulation of mitochondrial ATP synthesis coupled electron transport →	+0.105	+1.089	<.001	.001	3	11
OVARY	RNA 3'-end processing →	+0.063	+0.704	.001	<.001	3	10
LUNG_NSCLC_LUAD	Protein localization to nuclear inner membrane →	+0.109	+0.602	.001	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,684 associations by consensus.

Negative regulation of beige fat cell differentiation by YME1L1 expression — LARGE_INTESTINE

Explore this box plot interactively →