YME1L1

Across TCGA cell cohorts, YME1L1 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. OESOPHAGUS shows the largest number of these associations.

The most reproducible YME1L1-associated genes across cancer lineages are CABP2, FTMT, and OR2L5. Each is linked with YME1L1 in more than 1 cancer types. Because this analysis shows association rather than direction, both YME1L1-to-partner and partner-to-YME1L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CABP2 grouped by YME1L1-low versus YME1L1-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (YME1L1→partner) and Y-score (partner→YME1L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	CABP2 →	+0.058	+4.369	<.001	.008	3	1
SOFT_TISSUE	FTMT →	+0.065	+4.977	<.001	.002	3	1
SOFT_TISSUE	OR2L5 →	+0.011	+5.169	<.001	<.001	3	1
SOFT_TISSUE	RBMY1D →	+0.039	+4.369	<.001	.008	3	1
PANCREAS	SHCBP1L →	+0.005	+4.614	<.001	.004	3	1
PANCREAS	LALBA →	+0.019	+4.786	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

CABP2 by YME1L1 expression — SOFT_TISSUE

Explore this box plot interactively →