YJU2

Across TCGA patient cohorts, YJU2 mutation is significantly associated with the RNA expression of many other genes, with 180 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible YJU2-associated genes across cancer lineages are OR5M2P, MIR6895, and MIR8075. Each is linked with YJU2 in more than 1 cancer types. Because this analysis shows association rather than direction, both YJU2-to-partner and partner-to-YJU2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR5M2P grouped by YJU2-low versus YJU2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (YJU2→partner) and Y-score (partner→YJU2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	OR5M2P →	+1.214	+5.328	<.001	.003	3	2
UCEC	MIR6895 →	+1.123	+3.088	<.001	.002	3	1
UCEC	MIR8075 →	+1.290	+3.448	<.001	<.001	3	1
SKCM	LINC02622 →	+0.079	+4.680	<.001	.007	3	1
SKCM	MIR5585 →	+0.605	+4.268	.001	.008	3	1
UCEC	ZMYND19 →	+0.623	+3.354	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 180 associations by consensus.

OR5M2P by YJU2 expression — SKCM

Explore this box plot interactively →