YJU2

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, YJU2 mutation is significantly associated with the immune_cell of many other genes, with 5 significant associations in total. COAD shows the largest number of these associations.

The most reproducible YJU2-associated genes across cancer lineages are CD4+ Tem, Neutrophils, and Preadipocytes. Each is linked with YJU2 in more than 2 cancer types. Because this analysis shows association rather than direction, both YJU2-to-partner and partner-to-YJU2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD4+ Tem grouped by YJU2-low versus YJU2-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (YJU2→partner) and Y-score (partner→YJU2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCACD4+ Tem →+0.028+5.234<.001.03833
COADNeutrophils →+0.028+3.564<.001.02733
BRCAPreadipocytes →+0.049+4.079<.001.03131
COADMonocytes →+0.035+5.149<.001.03631
UCECEosinophils →+0.083+3.354.003.00531
Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

CD4+ Tem by YJU2 expression — BRCA

Box plot of CD4+ Tem in YJU2-low vs YJU2-high samples in BRCA.

Explore this box plot interactively →

Exploration