YJEFN3

Across TCGA patient cohorts, YJEFN3 mutation is significantly associated with the RNA expression of many other genes, with 32 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible YJEFN3-associated genes across cancer lineages are RNU6-366P, LINC00208, and RNA5SP513. Each is linked with YJEFN3 in more than 1 cancer types. Because this analysis shows association rather than direction, both YJEFN3-to-partner and partner-to-YJEFN3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-366P grouped by YJEFN3-low versus YJEFN3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (YJEFN3→partner) and Y-score (partner→YJEFN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-366P →	+0.719	+6.226	<.001	.001	3	2
SKCM	LINC00208 →	+0.016	+5.624	<.001	.002	3	1
SKCM	RNA5SP513 →	+0.264	+4.970	<.001	.005	3	1
SKCM	RNU11-3P →	+0.287	+4.188	.008	.009	3	1
UCEC	RN7SL468P →	+0.349	+6.123	<.001	.002	3	1
UCEC	MIR548AQ →	+1.226	+5.031	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 32 associations by consensus.

RNU6-366P by YJEFN3 expression — UCEC

Explore this box plot interactively →