YIPF7

Across TCGA patient cohorts, YIPF7 mutation is significantly associated with the RNA expression of many other genes, with 586 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible YIPF7-associated genes across cancer lineages are GOLGA2, SH3GLB1, and IGHD6-6. Each is linked with YIPF7 in more than 1 cancer types. Because this analysis shows association rather than direction, both YIPF7-to-partner and partner-to-YIPF7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GOLGA2 grouped by YIPF7-low versus YIPF7-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (YIPF7→partner) and Y-score (partner→YIPF7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GOLGA2 →	+0.584	+3.218	<.001	.009	3	2
UCEC	SH3GLB1 →	+0.523	+3.480	.002	.002	3	2
HNSC	IGHD6-6 →	+1.332	+4.320	.001	.007	3	2
LUSC	MIR758 →	+0.261	+5.596	<.001	.001	3	2
UCEC	MON1B →	+0.620	+3.513	<.001	.002	3	2
UCEC	CEP104 →	+0.605	+3.480	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 586 associations by consensus.

GOLGA2 by YIPF7 expression — UCEC

Explore this box plot interactively →