YIPF7

Across TCGA cell cohorts, YIPF7 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible YIPF7-associated genes across cancer lineages are CFHR2, UBQLN3, and SPATA8. Each is linked with YIPF7 in more than 1 cancer types. Because this analysis shows association rather than direction, both YIPF7-to-partner and partner-to-YIPF7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CFHR2 grouped by YIPF7-low versus YIPF7-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (YIPF7→partner) and Y-score (partner→YIPF7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	CFHR2 →	+0.057	+5.357	<.001	.001	3	2
LUNG_NSCLC_LUAD	UBQLN3 →	+0.006	+4.734	.002	.002	3	1
BLOOD_Lymphoma	SPATA8 →	+0.203	+4.867	<.001	.009	3	1
LARGE_INTESTINE	STATH →	+0.225	+2.925	<.001	.007	3	1
LARGE_INTESTINE	GFRA2 →	+0.053	+3.665	<.001	.004	3	1
LARGE_INTESTINE	NPY2R →	+0.003	+3.217	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

CFHR2 by YIPF7 expression — CNS

Explore this box plot interactively →