YIPF4

Across TCGA patient cohorts, YIPF4 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,422 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible YIPF4-associated proteins across cancer lineages are RPS6, CASP4, and EPS15_S221. Each is linked with YIPF4 in more than 4 cancer types. Because this analysis shows association rather than direction, both YIPF4-to-partner and partner-to-YIPF4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, YIPF4 versus RPS6 in GBM, with a Pearson correlation of -0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (YIPF4→partner) and Y-score (partner→YIPF4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RPS6 →	-0.533	-0.409	<.001	<.001	3	5
GBM	CASP4 →	-0.480	-0.266	.001	.006	3	5
GBM	EPS15_S221 →	-0.402	-0.326	<.001	.001	3	5
CCRCC	PSME2 →	-0.381	-0.276	<.001	<.001	3	5
PDAC	RING1 →	+0.345	+0.235	<.001	.001	3	4
OV	ROCK2 →	+0.198	+0.403	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,422 associations by consensus.

YIPF4 vs RPS6 — GBM

Explore this scatter interactively →