YIPF4

Across TCGA patient cohorts, YIPF4 mutation is significantly associated with the RNA expression of many other genes, with 1,018 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible YIPF4-associated genes across cancer lineages are CCL5, CWC25, and TAF9. Each is linked with YIPF4 in more than 1 cancer types. Because this analysis shows association rather than direction, both YIPF4-to-partner and partner-to-YIPF4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCL5 grouped by YIPF4-low versus YIPF4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (YIPF4→partner) and Y-score (partner→YIPF4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CCL5 →	+1.192	+3.475	.003	.002	3	1
UCEC	CWC25 →	+0.521	+3.839	.001	<.001	3	1
UCEC	TAF9 →	+0.829	+3.343	<.001	.005	3	1
UCEC	RNA5SP414 →	+0.576	+2.255	<.001	.009	3	1
UCEC	IGHV2-70 →	+1.795	+3.807	.001	<.001	3	1
UCEC	CCL4L2 →	+1.067	+3.601	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,018 associations by consensus.

CCL5 by YIPF4 expression — UCEC

Explore this box plot interactively →