YIPF3

Across TCGA patient cohorts, YIPF3 mutation is significantly associated with the RNA expression of many other genes, with 388 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible YIPF3-associated genes across cancer lineages are SCGB1C2, NRBF2P3, and TTTY14. Each is linked with YIPF3 in more than 1 cancer types. Because this analysis shows association rather than direction, both YIPF3-to-partner and partner-to-YIPF3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SCGB1C2 grouped by YIPF3-low versus YIPF3-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (YIPF3→partner) and Y-score (partner→YIPF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	SCGB1C2 →	+0.165	+4.910	.001	.002	3	2
UCEC	NRBF2P3 →	+0.121	+2.174	.002	.006	3	2
CESC	TTTY14 →	+0.012	+4.345	.009	.002	3	1
CESC	RNA5SP307 →	+0.174	+4.757	<.001	.004	3	1
CESC	RNA5SP485 →	+0.292	+4.384	<.001	.008	3	1
CESC	RNU6-432P →	+0.223	+4.559	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 388 associations by consensus.

SCGB1C2 by YIPF3 expression — COAD

Explore this box plot interactively →