YIPF3

Across TCGA cell cohorts, YIPF3 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible YIPF3-associated genes across cancer lineages are SLC5A8, KRTAP2-4, and SCRT2. Each is linked with YIPF3 in more than 1 cancer types. Because this analysis shows association rather than direction, both YIPF3-to-partner and partner-to-YIPF3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC5A8 grouped by YIPF3-low versus YIPF3-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (YIPF3→partner) and Y-score (partner→YIPF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	SLC5A8 →	+0.627	+4.095	<.001	.009	3	1
SKIN	KRTAP2-4 →	+0.036	+4.415	<.001	.007	3	1
SKIN	SCRT2 →	+0.006	+4.095	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

SLC5A8 by YIPF3 expression — LARGE_INTESTINE

Explore this box plot interactively →