YIPF2

Across TCGA patient cohorts, YIPF2 mutation is significantly associated with the RNA expression of many other genes, with 49 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible YIPF2-associated genes across cancer lineages are RN7SKP154, LINC00433, and KRT18P46. Each is linked with YIPF2 in more than 1 cancer types. Because this analysis shows association rather than direction, both YIPF2-to-partner and partner-to-YIPF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP154 grouped by YIPF2-low versus YIPF2-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (YIPF2→partner) and Y-score (partner→YIPF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RN7SKP154 →	+0.143	+5.289	<.001	.003	3	1
BLCA	LINC00433 →	+0.035	+5.618	.002	.002	3	1
BLCA	KRT18P46 →	+0.111	+4.331	.003	.007	3	1
UCEC	RNA5SP414 →	+0.802	+3.255	<.001	.003	3	1
UCEC	MIR6768 →	+0.846	+3.953	.003	.002	3	1
SKCM	NUDT19P4 →	+0.091	+5.680	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 49 associations by consensus.

RN7SKP154 by YIPF2 expression — BLCA

Explore this box plot interactively →