YIPF2

Across TCGA cell cohorts, YIPF2 mutation is significantly associated with the RNA expression of many other genes, with 42 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible YIPF2-associated genes across cancer lineages are GYS2, OR52H1, and TRARG1. Each is linked with YIPF2 in more than 1 cancer types. Because this analysis shows association rather than direction, both YIPF2-to-partner and partner-to-YIPF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GYS2 grouped by YIPF2-low versus YIPF2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (YIPF2→partner) and Y-score (partner→YIPF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	GYS2 →	+0.039	+3.345	<.001	.007	3	1
LARGE_INTESTINE	OR52H1 →	+0.020	+3.347	.003	.005	3	1
LARGE_INTESTINE	TRARG1 →	+0.022	+3.345	<.001	.007	3	1
BLOOD_Leukemia	ISM2 →	+0.264	+3.379	.001	.006	3	1
BLOOD_Leukemia	SLC32A1 →	+0.689	+3.486	<.001	<.001	3	1
BLOOD_Leukemia	PHOX2B →	+0.020	+3.966	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 42 associations by consensus.

GYS2 by YIPF2 expression — LARGE_INTESTINE

Explore this box plot interactively →