YIF1B

Across TCGA pan-cancer cohorts, YIF1B mass-spec protein differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of YIF1B’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where YIF1B mass-spec protein is repressed in tumor relative to normal tissue. In most cancer types YIF1B is over-expressed in tumor, although a few such as LUAD show the opposite, repressed pattern.

LUAD, CCRCC, and PDAC are the cancer types where YIF1B tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in YIF1B mass-spec protein (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Female	All	−0.267	<.001	5	view →
CCRCC	Female	All	+0.650	.008	4	view →
PDAC	Male	All	+0.376	.039	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

YIF1B–LUAD

Open the LUAD breakdown →