YIF1A

Across TCGA pan-cancer cohorts, YIF1A mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated YIF1A data layer compared with 24 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher YIF1A mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated YIF1A expression acts as an unfavorable survival marker.

LSCC, HNSC, and PDAC are the cancer types where YIF1A mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	OS	Quartile	II,III,IV	0.635	1.000	.003	33	view →
HNSC	OS	Median	IV	0.134	1.000	.008	25	view →
PDAC	OS	Quartile	All	0.269	0.505	.025	4	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

YIF1A–LSCC (OS)

Open the LSCC breakdown →