YIF1A

Across TCGA patient cohorts, YIF1A mutation is significantly associated with the RNA expression of many other genes, with 1,069 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible YIF1A-associated genes across cancer lineages are RPL26P3, RN7SKP72, and MIR624. Each is linked with YIF1A in more than 1 cancer types. Because this analysis shows association rather than direction, both YIF1A-to-partner and partner-to-YIF1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPL26P3 grouped by YIF1A-low versus YIF1A-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (YIF1A→partner) and Y-score (partner→YIF1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RPL26P3 →	+0.267	+3.754	<.001	.008	3	2
COAD	RN7SKP72 →	+0.224	+4.807	.005	.004	3	1
COAD	MIR624 →	+0.553	+3.717	.006	.008	3	1
COAD	TRDJ4 →	+0.633	+4.537	<.001	.006	3	1
COAD	RPL23P4 →	+0.188	+4.321	<.001	.002	3	1
COAD	UBE2D3P4 →	+0.237	+6.306	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,069 associations by consensus.

RPL26P3 by YIF1A expression — COAD

Explore this box plot interactively →