YIF1A

Across TCGA cell cohorts, YIF1A RNA expression is significantly associated with the go_rna of many other GO terms, with 3,443 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible YIF1A-associated GO terms across cancer lineages are CAAX-box protein processing, Negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway, and Establishment of protein localization to membrane. Each is linked with YIF1A in more than 12 cancer types. Because this analysis shows association rather than direction, both YIF1A-to-partner and partner-to-YIF1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CAAX-box protein processing grouped by YIF1A-low versus YIF1A-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (YIF1A→partner) and Y-score (partner→YIF1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	CAAX-box protein processing →	+0.116	+0.690	<.001	<.001	3	13
BONE	Negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway →	+0.226	+0.800	<.001	<.001	3	10
BLOOD_Lymphoma	Establishment of protein localization to membrane →	+0.063	+0.786	<.001	<.001	3	9
BONE	Negative regulation of response to endoplasmic reticulum stress →	+0.101	+0.714	<.001	<.001	3	9
BONE	Endoplasmic reticulum organization →	+0.069	+0.546	.001	.004	3	9
LUNG_NSCLC_LUSC	Protein retention in ER lumen →	+0.117	+0.711	.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,443 associations by consensus.

CAAX-box protein processing by YIF1A expression — BREAST

Explore this box plot interactively →