YIF1A

Across TCGA cell cohorts, YIF1A mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible YIF1A-associated genes across cancer lineages are RBMY1A1, AWAT2, and OR13C3. Each is linked with YIF1A in more than 1 cancer types. Because this analysis shows association rather than direction, both YIF1A-to-partner and partner-to-YIF1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RBMY1A1 grouped by YIF1A-low versus YIF1A-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (YIF1A→partner) and Y-score (partner→YIF1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	RBMY1A1 →	+0.143	+5.807	<.001	.001	3	1
BLOOD_Leukemia	AWAT2 →	+0.021	+4.705	<.001	.003	3	1
BLOOD_Leukemia	OR13C3 →	+0.025	+4.874	<.001	.002	3	1
LARGE_INTESTINE	DRD3 →	+0.012	+4.977	<.001	.007	3	1
LARGE_INTESTINE	CD300H →	+0.052	+5.415	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

RBMY1A1 by YIF1A expression — OVARY

Explore this box plot interactively →