YES1

Across TCGA patient cohorts, YES1 protein abundance is significantly associated with the RNA expression of many other genes, with 12,370 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible YES1-associated genes across cancer lineages are MYL12B, CHMP1B, and RALBP1. Each is linked with YES1 in more than 6 cancer types. Because this analysis shows association rather than direction, both YES1-to-partner and partner-to-YES1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, YES1 versus MYL12B in HNSC, with a Pearson correlation of 0.31.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (YES1→partner) and Y-score (partner→YES1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	MYL12B →	+1.514	+0.637	<.001	<.001	3	7
LUAD	CHMP1B →	+0.863	+0.496	<.001	<.001	3	7
HNSC	RALBP1 →	+0.838	+0.450	<.001	<.001	3	6
COAD	VAPA →	+0.589	+0.291	<.001	<.001	3	6
HNSC	AFG3L2 →	+0.843	+0.296	<.001	.005	3	6
BRCA	MYL12A →	+0.485	+0.519	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,370 associations by consensus.

YES1 vs MYL12B — HNSC

Explore this scatter interactively →