YEATS2

Across TCGA patient cohorts, YEATS2 RNA expression is significantly associated with the protein abundance of many other proteins, with 21,983 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible YEATS2-associated proteins across cancer lineages are FXR1, PLOD1, and PLOD2. Each is linked with YEATS2 in more than 7 cancer types. Because this analysis shows association rather than direction, both YEATS2-to-partner and partner-to-YEATS2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, YEATS2 versus FXR1 in LSCC, with a Pearson correlation of 0.75.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (YEATS2→partner) and Y-score (partner→YEATS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	FXR1 →	+0.596	+1.203	<.001	<.001	3	8
OV	PLOD1 →	+0.629	+0.918	<.001	<.001	3	7
CCRCC	PLOD2 →	+0.774	+0.421	<.001	<.001	3	7
LSCC	POLR2H →	+0.458	+0.895	<.001	<.001	3	7
BRCA	PUS7 →	+0.420	+0.437	.001	.006	3	7
UCEC	MCM2_S139 →	+0.792	+0.546	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,983 associations by consensus.

YEATS2 vs FXR1 — LSCC

Explore this scatter interactively →