YEATS2

Across TCGA patient cohorts, YEATS2 protein abundance is significantly associated with the RNA expression of many other genes, with 13,132 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible YEATS2-associated genes across cancer lineages are ZZZ3, SNHG29, and NIPBL. Each is linked with YEATS2 in more than 5 cancer types. Because this analysis shows association rather than direction, both YEATS2-to-partner and partner-to-YEATS2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, YEATS2 versus ZZZ3 in LSCC, with a Pearson correlation of 0.68.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (YEATS2→partner) and Y-score (partner→YEATS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ZZZ3 →	+0.544	+0.268	<.001	<.001	3	6
BRCA	SNHG29 →	+0.603	+0.185	.001	<.001	3	5
LSCC	NIPBL →	+0.510	+0.198	<.001	<.001	3	5
LSCC	SCML2 →	+0.883	+0.192	<.001	<.001	3	4
LSCC	RPL22 →	+0.468	+0.220	<.001	<.001	3	4
GBM	ITGB3BP →	+0.563	+0.330	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,132 associations by consensus.

YEATS2 vs ZZZ3 — LSCC

Explore this scatter interactively →