YEATS2

Across TCGA cell cohorts, YEATS2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,741 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible YEATS2-associated GO terms across cancer lineages are Epigenetic regulation of gene expression, Regulation of mRNA catabolic process, and DNA-templated transcription initiation. Each is linked with YEATS2 in more than 17 cancer types. Because this analysis shows association rather than direction, both YEATS2-to-partner and partner-to-YEATS2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Epigenetic regulation of gene expression grouped by YEATS2-low versus YEATS2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (YEATS2→partner) and Y-score (partner→YEATS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Epigenetic regulation of gene expression →	+0.076	+0.800	<.001	<.001	3	18
KIDNEY	Regulation of mRNA catabolic process →	+0.060	+0.915	<.001	<.001	3	16
BONE	DNA-templated transcription initiation →	+0.096	+0.924	<.001	<.001	3	16
LUNG_SCLC	Negative regulation of gene expression, epigenetic →	+0.111	+1.103	<.001	<.001	3	16
BONE	Regulation of double-strand break repair via homologous recombination →	+0.108	+0.778	.007	.009	2	16
BLOOD_Myeloma	Import into nucleus →	+0.080	+0.747	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,741 associations by consensus.

Epigenetic regulation of gene expression by YEATS2 expression — BONE

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