YBX3

Across TCGA patient cohorts, YBX3 mutation is significantly associated with the RNA expression of many other genes, with 1,969 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible YBX3-associated genes across cancer lineages are SNORD115-45, RNU7-90P, and RN7SL808P. Each is linked with YBX3 in more than 1 cancer types. Because this analysis shows association rather than direction, both YBX3-to-partner and partner-to-YBX3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNORD115-45 grouped by YBX3-low versus YBX3-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (YBX3→partner) and Y-score (partner→YBX3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	SNORD115-45 →	+0.376	+4.771	<.001	.006	3	2
UCEC	RNU7-90P →	+0.194	+2.379	.002	.008	3	2
UCEC	RN7SL808P →	+0.049	+3.484	<.001	<.001	3	2
LUSC	MIR2467 →	+0.566	+4.035	.001	.003	3	2
SKCM	RPL12P40 →	+0.079	+4.594	<.001	.008	3	2
BLCA	NMD3P2 →	+0.053	+4.973	.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,969 associations by consensus.

SNORD115-45 by YBX3 expression — SKCM

Explore this box plot interactively →