YBX3

Across TCGA cell cohorts, YBX3 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible YBX3-associated genes across cancer lineages are UTF1, ADH1A, and FAM205A. Each is linked with YBX3 in more than 1 cancer types. Because this analysis shows association rather than direction, both YBX3-to-partner and partner-to-YBX3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, UTF1 grouped by YBX3-low versus YBX3-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (YBX3→partner) and Y-score (partner→YBX3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	UTF1 →	+0.015	+3.217	<.001	.006	3	1
LARGE_INTESTINE	ADH1A →	+0.155	+3.242	<.001	.003	3	1
LARGE_INTESTINE	FAM205A →	+0.028	+4.029	<.001	<.001	3	1
BLOOD_Lymphoma	AVP →	+0.031	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	DYNAP →	+0.071	+4.867	.002	.009	3	1
LARGE_INTESTINE	PBOV1 →	+0.069	+3.333	<.001	.009	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

UTF1 by YBX3 expression — LARGE_INTESTINE

Explore this box plot interactively →