YBX2

Across TCGA patient cohorts, YBX2 mutation is significantly associated with the RNA expression of many other genes, with 241 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible YBX2-associated genes across cancer lineages are RN7SL219P, ARHGAP27P2, and ZBTB7A. Each is linked with YBX2 in more than 1 cancer types. Because this analysis shows association rather than direction, both YBX2-to-partner and partner-to-YBX2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL219P grouped by YBX2-low versus YBX2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (YBX2→partner) and Y-score (partner→YBX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL219P →	+0.388	+2.177	<.001	.008	3	1
UCEC	ARHGAP27P2 →	+0.800	+3.700	.003	.001	3	1
UCEC	ZBTB7A →	+0.420	+2.606	.002	.006	3	1
UCEC	PRF1 →	+1.205	+3.721	<.001	<.001	3	1
UCEC	SLC25A18 →	+0.336	+3.721	.002	<.001	3	1
UCEC	RPS27L →	+0.634	+3.459	.003	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 241 associations by consensus.

RN7SL219P by YBX2 expression — UCEC

Explore this box plot interactively →