YBX2

Across TCGA cell cohorts, YBX2 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible YBX2-associated genes across cancer lineages are PTH, OR52K2, and NKX2-6. Each is linked with YBX2 in more than 1 cancer types. Because this analysis shows association rather than direction, both YBX2-to-partner and partner-to-YBX2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PTH grouped by YBX2-low versus YBX2-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (YBX2→partner) and Y-score (partner→YBX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	PTH →	+0.023	+6.247	<.001	<.001	3	1
BLOOD_Lymphoma	OR52K2 →	+0.012	+5.209	<.001	.005	3	1
BLOOD_Leukemia	NKX2-6 →	+0.591	+5.201	<.001	.006	3	1
BLOOD_Leukemia	TLE7 →	+0.042	+5.969	<.001	.001	3	1
LARGE_INTESTINE	OR4F5 →	+0.024	+3.345	<.001	.007	3	1
LARGE_INTESTINE	ARGFX →	+0.010	+4.022	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

PTH by YBX2 expression — BLOOD_Lymphoma

Explore this box plot interactively →