Across TCGA pan-cancer cohorts, YBX1P9 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of YBX1P9’s most consistent transcriptional readouts.
The strongest signal is observed in thyroid carcinoma (THCA), where YBX1P9 RNA is repressed in tumor relative to normal tissue. In most cancer types YBX1P9 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.
THCA and KIRC are the cancer types where YBX1P9 tumor–normal differential expression is most reproducible.