Across TCGA pan-cancer cohorts, YBX1P8 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of YBX1P8’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where YBX1P8 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types YBX1P8 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

LUSC, STAD, and LUAD are the cancer types where YBX1P8 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in YBX1P8 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	All	All	+0.044	.001	4	view →
STAD	All	All	+0.093	.004	3	view →
LUAD	All	All	+0.136	.015	2	view →
CHOL	All	All	+0.124	.004	2	view →
THCA	All	All	−0.022	.014	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: YBX1P8 RNA expression & survival · all YBX1P8 data types