YBX1

Across TCGA cell cohorts, YBX1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,475 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible YBX1-associated GO terms across cancer lineages are Mitotic spindle midzone assembly, DNA replication initiation, and DNA replication checkpoint signaling. Each is linked with YBX1 in more than 16 cancer types. Because this analysis shows association rather than direction, both YBX1-to-partner and partner-to-YBX1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitotic spindle midzone assembly grouped by YBX1-low versus YBX1-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (YBX1→partner) and Y-score (partner→YBX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Mitotic spindle midzone assembly →	+0.244	+1.209	<.001	<.001	3	17
BONE	DNA replication initiation →	+0.197	+0.804	.003	.002	3	17
BONE	DNA replication checkpoint signaling →	+0.200	+0.698	.001	.003	3	17
PANCREAS	Mitotic spindle elongation →	+0.244	+1.209	<.001	<.001	3	17
BLOOD_Myeloma	Nuclear pore localization →	+0.200	+0.986	<.001	<.001	3	17
PANCREAS	Spindle elongation →	+0.203	+0.892	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,475 associations by consensus.

Mitotic spindle midzone assembly by YBX1 expression — PANCREAS

Explore this box plot interactively →