YBEY

Across TCGA pan-cancer cohorts, YBEY mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated YBEY data layer compared with 26 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher YBEY mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated YBEY expression acts as an unfavorable survival marker, although some lineages such as LSCC and CCRCC show a favorable association.

LSCC, CCRCC, and GBM are the cancer types where YBEY mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	DFS	Median	II,III,IV	1.000	0.485	.013	8	view →
CCRCC	DFS	Tertile	All	0.979	0.392	.007	5	view →
GBM	OS	Quartile	All	0.997	0.882	.025	2	view →
LUAD	DFS	Median	All	0.520	0.756	.017	2	view →
PDAC	DFS	Median	III,IV	0.278	0.545	.047	2	view →
HNSC	DFS	Tertile	III,IV	1.000	0.904	.018	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

YBEY–LSCC (DFS)

Open the LSCC breakdown →