YBEY

Across TCGA patient cohorts, YBEY mutation is significantly associated with the RNA expression of many other genes, with 46 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible YBEY-associated genes across cancer lineages are MIR525, RNU6-543P, and RNU6-776P. Each is linked with YBEY in more than 1 cancer types. Because this analysis shows association rather than direction, both YBEY-to-partner and partner-to-YBEY results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR525 grouped by YBEY-low versus YBEY-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (YBEY→partner) and Y-score (partner→YBEY) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MIR525 →	+0.561	+7.731	<.001	.009	3	2
BRCA	RNU6-543P →	+0.283	+8.055	<.001	.007	3	1
BRCA	RNU6-776P →	+0.282	+8.471	<.001	.005	3	1
BRCA	RNU6-278P →	+0.272	+7.731	<.001	.009	3	1
BRCA	MIR1197 →	+0.467	+7.731	<.001	.009	3	1
BRCA	RNU2-47P →	+0.628	+8.055	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 46 associations by consensus.

MIR525 by YBEY expression — BRCA

Explore this box plot interactively →