YBEY

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, YBEY mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible YBEY-associated genes across cancer lineages are MEP, lymphatic Endothelial cells, and Megakaryocytes. Each is linked with YBEY in more than 1 cancer types. Because this analysis shows association rather than direction, both YBEY-to-partner and partner-to-YBEY results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MEP grouped by YBEY-low versus YBEY-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (YBEY→partner) and Y-score (partner→YBEY) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMEP →+0.036+3.010.026.02031
UCEClymphatic Endothelial cells →-0.028-2.946.039.03711
UCECMegakaryocytes →-0.030-2.957.037.03711
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

MEP by YBEY expression — UCEC

Box plot of MEP in YBEY-low vs YBEY-high samples in UCEC.

Explore this box plot interactively →

Exploration