YARS2

Across TCGA patient cohorts, YARS2 protein abundance is significantly associated with the RNA expression of many other genes, with 16,615 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible YARS2-associated genes across cancer lineages are CNRIP1, TPSAB1, and GNG2. Each is linked with YARS2 in more than 7 cancer types. Because this analysis shows association rather than direction, both YARS2-to-partner and partner-to-YARS2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, YARS2 versus CNRIP1 in OV, with a Pearson correlation of -0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (YARS2→partner) and Y-score (partner→YARS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CNRIP1 →	-0.875	-0.522	<.001	<.001	3	8
BRCA	TPSAB1 →	-1.244	-0.339	<.001	<.001	3	7
BRCA	GNG2 →	-0.826	-0.356	<.001	<.001	3	7
BRCA	TPSB2 →	-1.201	-0.331	<.001	<.001	3	7
COAD	TNFSF12 →	-0.797	-0.382	<.001	<.001	3	7
OV	ARHGAP31 →	-0.869	-0.476	<.001	.002	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,615 associations by consensus.

YARS2 vs CNRIP1 — OV

Explore this scatter interactively →