YARS1

Across TCGA patient cohorts, YARS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,272 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible YARS1-associated proteins across cancer lineages are MRTO4, NCAPD2, and CDC20_T70. Each is linked with YARS1 in more than 6 cancer types. Because this analysis shows association rather than direction, both YARS1-to-partner and partner-to-YARS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, YARS1 versus MRTO4 in CCRCC, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (YARS1→partner) and Y-score (partner→YARS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	MRTO4 →	+0.351	+0.387	<.001	.001	3	7
BRCA	NCAPD2 →	+0.639	+0.561	<.001	<.001	3	7
LUAD	CDC20_T70 →	+0.978	+0.336	.002	.002	3	7
LSCC	HAT1 →	+0.398	+0.435	.009	<.001	3	7
BRCA	PURA →	-0.315	-0.448	.002	.001	3	7
BRCA	TNS2 →	-0.350	-0.430	.001	.003	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,272 associations by consensus.

YARS1 vs MRTO4 — CCRCC

Explore this scatter interactively →